Long-term effects of LEM on immune function in hemophiliac patients infected with HIV

University of Occupational and Environmental Health

[Details]
Among seven cases of hemophiliac patients infected with HIV who received LEM, five patients with hemophilia A taking LEM for at least four years were investigated. LEM was administered three times a day for a total dose of 9 grams.
 
[Results]
LEM was administered in four out of five cases with decent medication adherence, and despite over four years of observation, neither a decline in CD4 nor adverse effects were observed, suggesting the long-term effectiveness of LEM against HIV infection.