LEM inhibits virus proliferation

Graduate School,University of Tsukuba

Infuruence on infection by inhuruenza
A virus-Protecting host cells from viral infection
 
It was examined whether LEM has an effect of protecting cells from infection by the influenza virus. Influenza A virus was mixed into the LEM solution of a specified concentration. The mixed solution was added to cells to test their infectivity through the plaque assay. The results indicated that the plaques were LEM concentration-dependently reduced in number, suggesting the effect of protecting host cells from viral influenza infection.
 
Influence of LEM on the size of the plaques
A virus - Reducing the viral replication process
 
It was examined whether LEM has an effect of reducing the influenza viral replication process. Cells were namely infected with influenza A virus, and then LEM solution of a specified concentration was added to the infected cells. The expansion of plaques was tested through the plaque assay. The results showed that the plaques were LEM concentration-dependently reduced in size, suggesting the effect of reducing the influenza viral replication process, and of reducing multiplication as a result.