NSK Co., Ltd.
担子菌培養抽出物のパイオニア

LEM論文発表
[直近20報告]

シイタケ菌糸体培養培地抽出物

  1. 小早川幸子ら (2018) 椎茸菌糸体培養培地抽出物(LEM)由来水溶性リグニン画分(JLS-18)の抗アレルギー効果. New food industry 60. 42–48
  2.  Kuroki T. et al. (2018) Inhibition of Influenza Virus Infection by Lentinus edodes Mycelia Extract Through Its Direct Action and Immunopotentiating Activity. Frontiers in microbiology 9.
  3.  玄美燕ら (2017) 椎茸菌糸体培養培地抽出物の脳保護効果. New food industry 59. 1–14
  4. 堀内重紀ら (2016) 椎茸菌糸体培養培地抽出物(LEM)の神経保護作用. New food industry 58. 1–10
  5. Yamamoto Y. et al. (1997) Immunopotentiating Activity of the Water-soluble Lignin Rich Fraction Prepared from LEM -The Extract of the Solid Culture Medium of Lentinus edodes Mycelia. Bioscience, Biotechnology, and Biochemistry 61. 1909–1912
  6. 大橋康宏 (1996) 椎茸菌糸体培養抽出物「LEM」の生理作用. 月刊フ-ドケミカル 12. 56–61
  7. Morinaga H. et al. (1994) An in vivo Study of Hepatic and Splenic Interleukin-lβ mRNA Expression Following Oral PSK or LEM Administration. Japanese Journal of Cancer Research 85. 1298–1303
  8. Hibino Y. et al. (1994) Productions of interferon-γ and nitrite are induced in mouse splenic cells by a heteroglycan-protein fraction from culture medium of Lentinus edodes mycelia. Immunopharmacology 28. 77–85
  9. Sarkar S. et al. (1993) Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1. Antiviral Research 20. 293–303
  10. Kajihara J. et al. (1993) Characterization of Antiviral Water-Soluble Lignin from Bagasse Degraded by Lentinus edodes. Holzforshung 47. 479–485
  11.  Hattori T. et al. (1993) Formate and Oxalate Esters in Lignin Obtained from Bagasse Degraded by Lentinus edodes. 木材学会誌 39. 1317–1321
  12. 森永秀夫ら (1992) Lentinus edodes mycelia(LEM)の経口投与による肝転移抑制効果. Biotherapy 6. 763–765
  13. 溝口靖紘ら (1992) 肝類洞内皮細胞の血小板活性化因子産生に及ぼすLentinus edodes mycelia 培養抽出物 (LEM) の影響. 日本東洋医学雑誌 42. 307–311
  14. Tabata T. et al. (1992) Mitogenic activities of heteroglycan and heteroglycan-protein fractions from culture medium of Lentinus edodesmycelia. Immunopharmacology 24. 57–63
  15. 市川裕三ら (1991) 腹腔滲出マクロファージの細胞内遊離カルシウムイオン濃度に及ぼす椎茸（Lentinus edodes）菌糸体培養抽出物（LEM）の影響. 和漢医薬学会誌 8. 162–166
  16. 鈴木康將ら (1990) 椎茸菌糸体 (Lentinus Edodes Mycelia) の温水抽出物によるAzoxymethane誘発ラット大腸癌発生に対する抑制効果. 日本大腸肛門病学会雑誌 43. 178–191
  17. 白幡聡ら (1990) 多糖類によるHIV感染者の免疫改善効果. 免疫薬理 9. 103–106
  18. 華房徹ら (1990) 生物活性を持つ水溶性14-Cリグニンのラットにおける腸管吸収および体内動態. 薬物動態 5. 661–674
  19. Suzuki H. et al. (1990) Structural Characterization of the Immunoactive and Antiviral Water-solubilized Lignin in an Extract of the Culture Medium of Lentinus edodes Mycelia (LEM). Agricultural and Biological Chemistry 54. 479–487
  20. Sorimachi K. et al. (1990) Morphological Changes of Tumor Cells Caused by Macrophages Treated with Lignin Derivatives. Agricultural and Biological Chemistry 54. 1611–1613